Trusted by over 60 internationally recognised institutions
How it works
The Nurosym VNS Clinically Proven Mechanism
Energy Production Starts With Improved Brain Chemistry
Cytokines are tiny immune messengers—but when overproduced, they can shut down the brain’s ability to create and use energy. Nurosym helps keep it in check.
Originally designed to fight infection, cytokines like IL-6 and TNF-α can cross the blood-brain barrier and disrupt mitochondrial function in brain cells, leading to the hallmark symptoms of Chronic Fatigue Syndrome: brain fog, low motivation, and unrelenting exhaustion. Nurosym activates the vagus nerve’s anti-inflammatory reflex that reduces overproduction of these harmful cytokines and restores balance in brain chemistry.
Regaining Energy Levels Starts With Rebalancing the Nervous System
Over 90% of people with Chronic Fatigue Syndrome (CFS) show signs of autonomic nervous system (ANS) dysfunction (1). Your nervous system controls how energy is allocated throughout the body. In conditions like CFS, this system is often stuck in survival mode, draining energy instead of restoring it.
Nurosym is a neural reset tool that rebalances the ANS by gently stimulating the vagus nerve, helping shift the body out of chronic stress and into a state where healing and energy replenishment can occur—so you feel clearer, more energized, and more in control, without relying on stimulants or quick fixes.
Vagus Nerve Impairment - The Root Cause of Fatigue Symptoms
Your autonomic nervous system runs silently in the background—regulating everything from your heartbeat to your digestion. But when your sympathetic “fight-or-flight” system is stuck on, your body never gets the chance to rest, recharge, or repair.
Nurosym taps into the vagus nerve to restore parasympathetic balance—the body’s natural recovery mode—so your system can slow down, heal, and rebuild energy from within.
Parasympathetic Calm
- Calm focus
- Deep rest
- Energy recovery
Sympathetic Overdrive
- Constant tension
- Poor sleep
- Chronic tiredness
Session 1
Morning 30 min
Start your day in balance. Boost parasympathetic tone before the stress from work kicks in—supporting clearer thinking and calm energy.
Session 2-3
Afternoon & Evening 30 min
Recharge your nervous system during the day’s low point (optional). Do another session 1hr before bed to reduce brain fog, manage fatigue, and reset the stress cycle.
How To Use
Reset the System Your Energy Depends On
Unlike stimulants, Nurosym doesn’t force your brain to push harder—it teaches your nervous system to work better. By gently activating the vagus nerve, Nurosym helps restore balance, reduce inflammation, and support lasting energy from the inside out.
FRANCESCA, UK
“Honestly, I’ve seen such a big difference. I don’t have as many days where I’m so exhausted I can barely move”
The Nurosym VNS Clinically Proven Mechanism
48% Reduced in fatigue & increased energy
- Productivity
- Social Functioning
- Brain Fog Reduction
- Sleep Quality
- Pain Relief
- Long-Covid Symptoms
- Ageing & Longevity
Nurosym neuromodulation has demonstrated a beneficial effect on fatigue by modulating the autonomic nervous system, leading to enhanced energy levels and reduced sensations of exhaustion. In the study, patients reported sustained improvements even one week after discontinuing the therapy, indicating prolonged relief from fatigue-related symptoms.(Figure) Fatigue was assessed using the Pichot fatigue scale scores during therapy (D0: day 0, D5: day 5 and D10: day 10). The results revealed a substantial reduction in fatigue, registering approximately 48% improvement (D0 vs. D10, p < 0.0001) after Nurosym neuromodulation therapy.
SOURCE:
Clinical trial using Parasym proprietary neuromodulation technology, Independently evaluated and funded, published in the Advances in Neurology and Neuroscience Journal
Is Nurosym Right for You?
Do you often feel drained, even after a full night’s sleep?
Trusted by experts, loved by users
Nurosym's community brings together diverse journeys united by a shared goal - to support our nervous system and mental state.
Watch in-depth user stories
- Post Viral Fatigue
Relieving Post Viral Symptoms
"Five star rating for me. In this world where there's not much we can go on, this is one of the things we can."
Derek
- Inflammation
- Fatigue
- Sleep issues
Post-Viral Fatigue, Autoimmune Relief, and Better Sleep
“I definitely noticed when I haven't used it, I don't sleep as well.”...”when I don't use it, I feel a lot more inflamed and achy and just not well.”
Kate
- Fatigue
- Brain Fog
From Fatigue, Menstrual Pain to Clarity
"I've had a very good experience with it, and I'd recommend it to anybody who was hoping for relief, particularly from chronic tiredness and brain fog symptoms."
Tasha
- Anxious Thoughts
- Chronic Tiredness
- Stress
Managing Stress & Sleep with Nurosym: A Chronic Tiredness Success Story
"I actually would recommend this to my clients. So, it's a really interesting device, lots of research."
Ton
- Chronic Tiredness
- Pain
From Post-Viral Fatigue and Ongoing Tiredness to Nurosym Relief: A Life-Changing Experience
"I just want to spread the word and hope that other people can get access to Nurosym because it has made such a difference in my life and clearly a lot of others."
David
FREQUENTLY ASKED QUESTIONS
Some of your most asked questions, answered
Are there any side effects associated with Nurosym?
As with any device, side effects are possible, however, we're happy to report that Nurosym is considered low risk when used as intended and boasts a very high safety profile. In fact, across all 50+ scientific studies conducted, there have been no reports of serious adverse events associated with Nurosym in studies to date.
While side effects are rare, it's important to be aware of potential experiences. The most commonly reported side effects include:
- Tingling on the skin where the electrode is applied (paresthesia/dysesthesia)
- Discomfort on the skin of the ear (application site discomfort)
- Application site irritation/redness - if this occurs, try applying a bit of moisture before use, shorten session times, or switch ears
In the initial weeks of use, a small proportion of users may also experience temporary effects that typically subside within 1-2 weeks of continuous use due to adaptation. These effects may include nausea, headaches, confusion, malaise, or weakness.
It's worth noting that in a published review of non-invasive neuromodulation clinical studies, only 2.6% of users discontinued therapy due to side effects.
Can I use the Nurosym if I have an earring or a piercing?
We do not recommend using Nurosym if you have a piercing or an earring. We suggest removing the piercing, allowing the skin to fully heal up to a week, and then starting your use of Nurosym.
Can I share my Nurosym with others?
All Parasym clinical research has been conducted with each participant using their own personal device. To ensure the safest and most effective experience, we recommend that every individual user has their own device. Patient registration is done for each personal device to guarantee safe use.
Can I travel with my Nurosym?
Absolutely - in fact, Nurosym can help relieve inflammation related to high altitude and jet lag, making it the perfect travel companion. Just keep in mind that Nurosym is powered by lithium-ion batteries, so most air travel safety regulations require that it be carried in your carry-on baggage only. For added safety, we recommend checking your airport's guidelines or asking an airport employee before your flight.
Can I use Nurosym if I have a pacemaker or other medical implant?
Nurosym should not be used if you have any active implanted device, including electronic or medical devices such as a pacemaker, cochlear implant, cerebral shunts, or invasive vagus nerve stimulators. Additionally, if you have non-active implants that may potentially interact with the nervous system, such as metal implants, it's important to consult with your healthcare professional before using Nurosym. Users with known severe coronary disease or recent myocardial infarction (within 5 years), as well as pediatric patients, should also seek medical advice before using Nurosym.
Can I use Nurosym while sleeping or exercising?
We don’t recommend using Nurosym while sleeping or exercising. It's important to use Nurosym in a controlled environment where you can remain aware of its effects. Always prioritize your safety and well-being when using Nurosym.
Can Nurosym be used alongside other therapies or medications?
Nurosym can be a complementary tool alongside other therapies or medications for many individuals. However, there are specific contraindications to consider. These include:
- Users who have undergone surgery to cut the vagus nerve (cervical vagotomy)
- Users diagnosed with severe bradycardia
- Users with a permanent implanted metallic or electronic device or jewelry in close proximity to the ear tragus
- Pregnant women
Additionally, certain situations may be contraindications unless under the supervision of a healthcare professional, such as users with any active implanted device, severe coronary disease or recent myocardial infarction within 5 years, and pediatric users.
Can I use Nurosym while pregnant or breastfeeding?
We haven't evaluated the use of Nurosym in pregnant women during scientific studies. To ensure safety, we recommend consulting with your healthcare professional to determine if vagus nerve stimulation is appropriate for you during pregnancy or while breastfeeding.
What Does Nurosym Do
With Nurosym you can:
- Recover and activate your self-repair mechanisms by countering dysregulation in the nervous system.
- Build up your stress resilience, recover faster from stressful events and help prevent mood swings.
- Counter post-viral symptoms, like fatigue or brain fog.
- Maintain optimal HRV, recovery and reduce cardiovascular health risks.
- Relax and stabilise your mental state to help you fall asleep faster, achieve high-quality sleep, wake up more with more energy and fewer negative thoughts.
- Improve digestive function by promoting healthy communication through the gut-brain axis.
- Reduce inflammation, pain and discomfort linked to your nervous system.
- Strengthen cognitive performance & focus to counteract the effects of aging.
How does Nurosym achieve all of this?
Nurosym is a wearable device that sends electrical impulses to the brain via the vagus nerve to alleviate symptoms of dysregulated nervous system. Modern science has discovered that many chronic mental & physical symptoms are linked to chronically dysregulated nervous system. The nervous system and one of its largest nerves - the vagus nerve - controls all body functions, from breathing, heart rate, digestion to energy, calmness and mood. When the vagus nerve is not functioning properly, organs & systems of the body don’t work in harmony leading to poor physical & mental health. By strengthening the nervous system in a natural way through modulating the activity of the vagus nerve, Nurosym helps restore balance to the mind and body.
Nurosym exerts its effects through various mechanisms:
- It triggers the “rest and digest” response, promoting relaxation, lowering heart rate and improving digestion.
- Reduces inflammation markers leading linked to pain & overactive immune response
- Decreases oxidative stress markers linked to chronic diseases and ageing.
- Increases neuroplasticity, rewiring the brain for better mood, better motor & cognitive learning and recovery from neurological symptoms.
This way Nurosym supports mental & physical health and helps alleviate symptoms of a range of symptoms.
Nurosym is a certified wearable device delivering proprietary Auricular Vagal Neuromodulation Therapy (AVNT)™ developed by Parasym, scientifically validated and optimised in 50+ scientific studies conducted in partnership with leading scientific research institutions including Harvard and UCLA.
Nurosym is the only certified wearable device approved for the purpose of targeting the vagus nerve via the ear available without prescription. It is the most studied neuromodulation system of this kind, widely considered as the gold standard in scientific neuromodulation research.
Symptoms Studied
These symptoms have been linked to autonomic nervous system imbalance and Vagus Nerve Impairment:
- Anxious states and Stress related symptoms
- Chronic Tiredness, Fatigue, Brain Fog, Burnout
- Digestive issues, irritable gut reflux, diarrhoea, constipation, bloating
- Sleep problems
- Negative thoughts
- Inflammatory symptoms
- Pain, headaches
- Memory & Attention problems
- Postural Heart Rate Abnormalities or fainting
- Post-Viral Symptoms
- Widespread body pain
Our latest research data also suggests Nurosym improves learning and short-term memory and cognition.
Nurosym also has been shown to promote relaxation, mood, sleep, healthy digestion, increased HRV, as well as to alleviate symptoms of stress, burnout, adrenal fatigue.
Parasym research is also investigating the impact of Auricular Vagal Neuromodulation Therapy on athletic performance, muscle recovery, weight management problems, substance dependency and more.
If you’re not sure if Nurosym is for you consult with your health professional or contact our support by clicking the Support icon at the bottom right of the page.
Scientific Evidence & Research
Nurosym has partnered with 60+ research institutions, including UCLA and Harvard, to conduct scientific studies to validate the health benefits of Nurosym.
Our research is founded on these principles:
- Parasym’s studies are led by independent university experts, with no financial ties to us, unless explicitly mentioned.
- Our research is externally funded, ensuring unbiased and genuine results.
- We value transparency: All our study findings (positive or otherwise) are open and accessible to everyone.
- We collaborate with distinguished physicians and scientists, ensuring the pinnacle of research quality.
- At Parasym, we adhere to the highest scientific standards, consistently achieving significant and trustworthy results in the most stringent tests. A large part of our scientific evidence comes from Randomised Placebo-controlled Scientific Studies, which are considered the highest standard of evidence.
Results From Scientific Studies
Attività del nervo vago
Sintomi post virali
Stanchezza, nebbia cerebrale, sintomi gastrointestinali, dolore
Stanchezza
Sonno
Infiammazione
Variazione della frequenza cardiaca posturale
Variabilità della frequenza cardiaca
Punteggio depressivo
Stress ossidativo
Memoria
Lettura
Macrocircolazione
Microcircolo
Deficit di attenzione
Stati pensieri ansiosi
Palpitazioni
Funzione del muscolo cardiaco
Sintomi gastrointestinali
Risultati ottenuti in popolazioni di studi specifici. I risultati individuali possono variare.
How To Use
Guarda il Dr. Denef spiegare come usare Nurosym:
Come usare Nurosym in pochi passi:
- Applica un po' di umidità sul trago.
- Indossa correttamente l'auricolare sul tuo trago sinistro, il cavo dovrebbe passare sopra e dietro l'orecchio per mantenere gli elettrodi in posizione.
- Accendi Nurosym
Aumenta lentamente il livello di energia finché non senti una leggera sensazione di formicolio nell'orecchio. - Nota quanto sia piacevole la sensazione di neuromodulazione. Questo è un segnale che la corrente sta fluen do e che il tuo sistema nervoso parasimpatico è attivato
- Siediti o sdraiati con il dispositivo o svolgi le attività quotidiane mentre Nurosym lavora per rafforzare il tuo sistema nervoso parasimpatico, diminuire l'infiammazione, lo stress ossidativo e attivare la neuroplasticità per aiutarti a sentirti meglio.
- Nota le sensazioni di calma, rilassamento, riduzione dello stress, miglioramento dell'umore e più energia che fluisce nel tuo corpo.
- Se senti che la sensazione si intensifica nel tempo o smetti di sentirla, regola il livello di energia finché non senti di nuovo una leggera sensazione di formicolio piacevole.
- Continua a usare Nurosym ogni giorno per 30-60 minuti al giorno, preferibilmente al mattino o diviso tra mattina dopo il risveglio e sera prima di dormire, e goditi una migliore salute e umore.
Why Trust Nurosym
Gold standard in scientific research
- Nurosym is a certified medical device, with over $10M deployed in scientific research, 60+ partner research organisations including Harvard, UCLU, 50+ published papers in leading journals covering our exciting and scientifically significant results.
- This is why Nurosym is the leading non-invasive vagal neuromodulation system used in scientific neuromodulation research and now widely adopted.
Certified medical device (CE) in the EU with confirmed safety and FDA Non-Significant Risk Designation
Nurosym is a certified medical device (CE) in Europe. It has also received FDA Non-Significant Risk Designation in multiple studies in the US. This means:
- It has been audited by medical regulators
- It is based on rigorous scientific evidence
- The benefits outweighs the risks
- It has demonstrated scientific efficacy
- It has strict quality management systems
Be sure to read the important safety information before use.
- Exposing your nervous system and brain to untested electrical currents can put you at risk of a permanent damage to the brainstem and vagal nerve fibres, worsening your symptoms. Never use or suggest using DIY electrical current devices on your nervous system.
- Ensuring safety and efficacy requires extensive scientific studies that cost millions of dollars. This is why few neuromodulation devices have been certified by health regulatory bodies as safe and effective.
- Beware of websites claiming to deliver benefits from uncertified therapies that present online reviews instead of scientific evidence. Carefully verify if a therapy you’re evaluating is registered as a medical device, which certifies it is safe and effective to use.
- When considering any health intervention, be sure to evaluate the status of certification, scientific evidence, warnings and seek advice of trusted health care professionals.
- Nurosym is one of a few registered neuromodulation based medical devices with safety confirmed by regulatory bodies in EU in Randomised Placebo Controlled Studies.
Proven target activity
- In addition to safety, it is crucial to consider efficacy of various devices.
- The fact that a device is delivering a safe electrical current is not enough.It also needs to demonstrate that it indeed stimulates the right nerves and activates them. Triggering nerve action potential to fire requires precise waveform, frequency, wavelength and amplitude of electrical signal, as well as a specific stimulation site on the body closest to a particular branch of
- Without scientific data, we cannot know if a device is 1)actually stimulating the right neural pathways 2)not stimulating unintended neural pathway.
- Nurosym is demonstrated in scientific studies to stimulate the brainstem via the vagus nerve. Our patented waveform that exerts these effects has been developed over 8 years of laborious research with a total cost of over $10M.
Efficacy confirmed in Randomised Placebo Controlled Studies
- Many devices on the market claim benefits when combined with other practices such as meditation or breathing, which independently provide benefits such as relaxation, reduced anxious states, mood, stress, sleep. This fact makes it hard to discern whether claimed benefits are due to the device itself or the additional practice.
- What’s more placebo effect is a strong influencer on benefits of numerous devices. Only randomised placebo controlled scientific studies can demonstrate whether a device benefit is independent of the placebo effect. Make sure to verify quality of evidence provided by the manufacturer.
- Nurosym has demonstrated benefits independent of other practices in a number of Randomised Placebo Controlled Studies.
Contraindications
Nurosym is NOT recommended in the following cases for users:
- Undergone surgery to cut the vagus nerve (cervical vagotomy)
- Diagnosed with severe low resting heart rate
- Permanent implanted metallic/electronic device or jewellery at close proximity to the ear tragus (that cannot be removed before using Nurosym);
- Pregnant women.
Below are listed situations that are also contraindications unless the user receives a concrete health opinion on the device use by their health professional and is under the supervision of a health professional while using the device.
If you fall under one of these categories, your health professional might advise whether, in your specific case, the device is safe to use, potentially following certain precautions or under specific supervision:
- Users with any active implanted device (including electronic and/or medical devices) e.g. cochlear implant, cerebral shunts, invasive vagus nerve stimulators, pacemakers or non-active but potentially interacting with the nervous system (e.g. metal implants);
- Users with known severe coronary disease or recent heart attack (within 5 years);
- Paediatric users (children)
*Pregnant women have not been evaluated in scientific studies.
*Both paediatric users and users with pacemakers have been enrolled in scientific studies with Parasym technology, and no device related adverse events or interferences have been observed so far in the scientific setting.
Are there any ongoing research or studies about Nurosym?
Nurosym is at the forefront of scientific research, continuously investing substantial resources to advance neuromodulation technology. With over $10 million dedicated to studies, we collaborate with over 60 esteemed organizations, including Harvard and UCL, to deepen understanding and improve outcomes.
Our research has resulted in 50+ peer-reviewed papers in leading journals such as Nature and Nature Reviews Cardiology. This includes a meta-analysis of placebo-controlled cardiac studies in JACC, a highly reputable journal with a 21.7 impact factor, ranking among the world’s top 100 journals. These studies highlight exciting breakthroughs in modulating Vagus Nerve Activity, Heart Rate Variability, and more.
Are there any specific conditions that must be met for a return to be accepted?
In order for a return to be accepted, your item should be in its original condition and packaging, just as you received it.
Try risk-free for 30 days
Experience Nurosym at home and return it for a full refund if you don't love it
Certified medical device
Resets your resting state for deeper sleep and more daily energy
Worry-free warranty
Ongoing device protection for
up to 5 years.
Sources
1. Abhijit Chaudhuri
“Autonomic dysfunction in chronic fatigue syndrome”
QJM: An International Journal of Medicine, 2022