Experience Advanced Vagus Nerve Stimulation with Nurosym

Nurosym is clinically proven to boost your mood, increase energy levels, and optimize neurological health—right from your own home.

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Why Nurosym?

Nurosym is a sleek, easy-to-use wearable neuromodulation device designed to help you restore your health by targeting root issues in the body. It harnesses the power of advanced neuromodulation technology into a simple, safe, and effective handheld device that you can use right from your home. 

Most importantly, Nurosym is the most clinically studied non-invasive VNS device on the market. With validation by over 40 peer-reviewed studies and millions of treatment sessions, the device has demonstrated remarkable effectiveness in treating a host of chronic conditions in a safe and effective way.

Nurosym gives patients all the benefits of precise and controlled vagus nerve stimulation whenever needed, allowing anyone to move toward a healthier, more balanced life.

The science of vagus nerve stimulation

The vagus nerve, the longest and most complex cranial nerve, is a vital component of the parasympathetic nervous system. It extends from the brain to major organs like the heart, lungs, and intestines, and helps to maintain balance in the body by regulating essential processes such as heart rate and digestion.

The vagus nerve’s bidirectional communication with the central nervous system allows it to transmit sensory information and motor signals, ensuring the body functions smoothly. Even minor disruptions in vagus nerve function can significantly impact health, potentially leading to issues like depression, anxiety, and insomnia.

Doctors and researchers have explored the therapeutic benefits of stimulating the vagus nerve for decades. Vagus nerve stimulation works by sending precise electrical impulses to specific neural circuits, helping to rebalance the nervous system and improve overall physical and mental well-being. Similar to how a pacemaker regulates heart rhythms, vagus nerve stimulation aims to restore proper nervous system function. 

While early approaches relied on invasive procedures, recent advances in neuromodulation have delivered impressive clinical results through non-invasive methods. For example, the vagus nerve can be precisely stimulated through the ear tragus, which has the highest concentration of vagus nerve fibers near the surface of the skin.

Vagus nerve stimulation has shown remarkable promise in addressing underlying causes of various conditions, offering renewed hope for patients suffering from treatment-resistant health issues

Clinical Validation

Nurosym has demonstrated remarkable effectiveness in double-blind clinical trials and is utilized by trusted global leaders in the medical field including Harvard, UCL, and the Imperial College Healthcare NHS Trust.

The results from clinical trials, patient outcomes, and other reviews have found Nurosym to be a safe and effective solution for many symptoms associated with:

Mood and Mental Health

Depressive States

Anxious Thoughts

Low Mood

Cognitive Impairment

Energy and Resilience

Chronic Fatigue

Poor Sleep

Reduced Heart Rate Variability (HRV)

Post-Viral Fatigue

Pain and Inflammatory Conditions

Chronic Pain

Widespread Pain

Joint Pain

Inflammatory Conditions

Circulatory and Respiratory Health

Postural Heart Rate Abnormalities

Respiratory Issues

Low HRV

Digestive Health

Bloating

Gas

Acid Reflux

Nausea

Diarrhea

Abdominal Pain

How it Works

The vagus nerve is the longest cranial nerve in the body, extending from the brainstem down to the chest and abdomen, with connections to the heart, lungs, digestive tract, and other vital organs. It’s essentially a vital communication highway between the brain and key organs throughout the body, coordinating and regulating essential functions such as heart rate, digestion, immune responses, and mood stability. By maintaining this steady flow of information, the vagus nerve helps the body adapt to stress, process emotions, and support overall wellness, creating a balanced and resilient internal environment.

That’s why Nurosym can be used to target and alleviate symptoms of so many health conditions. By precisely stimulating the vagus nerve and improving vagus nerve function with Nurosym, patients are able to bring their entire body back into a state of harmony and balance.

Activates the Parasympathetic Nervous System & Reduces "Fight or Flight"

Nurosym engages the body’s relaxation response, helping to lower stress and anxiety levels. This helps promote restful sleep and also improves Heart Rate Variability (HRV), which is a key indicator of balance between the sympathetic (fight or flight) and parasympathetic (rest and digest) systems.

Reduces Inflammation

Nurosym helps to alleviate inflammation in the brain and body, which can ease symptoms associated with depression, chronic fatigue, and pain. Additionally, it strengthens the immune system and supports quicker recovery from injuries or infections.

Increases Neuroplasticity

Nurosym stimulates the brain’s ability to adapt and form new neural pathways, leading to long-term improvements in mood and mental health. This improved neuroplasticity helps "rewire" the brain and improve resilience, making patients’ recovery from chronic conditions more achievable. 



The device itself is also incredibly easy to use. Patients simply need to place the ear clip on their left ear and with one press of a button, the treatment session begins. From there, the intensity of the stimulation can be adjusted until a comfortable level is reached.

Most patients experience benefits in as little as 15 minutes of daily use for 5-10 days, but certain patients with more persistent conditions may require use up to 1 hour each day for several weeks or months for results. Given that Nurosym is portable, patients can easily complete their daily sessions while on-the-go or taking care of other household tasks.

Testimonials

Thanks to Nurosym’s remarkable VNS technology, thousands of people around the world have found relief from their chronic conditions and improved their overall health.

Michael

Hereford

After couple of weeks I suddenly realised, "I feel like me again." The depressive state has lifted and I have the get up and go, Thank you folks :)

Sarit

London

When I got the device, two days later, suddenly I had so much energy, I felt...something is good!

Pamela

Northhants

It has exceeded my expectations and I would happily recommend it to anyone with a diagnosed vagus nerve disorder and depression/anxiety.

Francesca

London

It's an amazing product. Honestly I've seen such a huge difference, I don't have as many days where I'm exhausted I can barely move.

Robert

Carlisle

While I can still have bad days, I'm much more stable and less prone to such destructive dips on mood.

Terry

Hove

I've looked into a number of approaches to reset my nervous system, the one that's given me the most obvious change is Nurosym.

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Endorsed by leading medical professionals and neuroscientists across the globe.

Thanks to its proven effectiveness in clinical trials, Nurosym has earned the trust and endorsement of leading medical professionals and institutions worldwide.

Experts recognize Nurosym for its ability to address the root causes of chronic conditions like anxiety, chronic fatigue, sleep issues, chronic pain, gut issues, and immune system disorders. Its non-invasive design and scientific backing make it a favored solution in clinics and research institutions across the globe, empowering patients to regain control of their health.

The support from distinguished institutions like Harvard University, UCLA, and UChicago Medicine, underscores Nurosym’s commitment to innovation and its transformative impact on patient health and wellness.

Nurosym vs. Other Vagus Nerve Stimulation Devices

When compared to other vagus nerve stimulation devices, Nurosym stands out as the most effective, portable, and user-friendly option on the market. Many VNS devices rely on bilateral neck stimulation, which is untested for efficacy and safety. The lack of robust clinical trials on these devices means that they might be a risk of severe cardiovascular side effects, stress reactions, and damage to the vagus nerve.

Other devices use chest vibration to indirectly stimulate the vagus nerve. The vagus nerve can be thought of as a communication highway where the language spoken is in electrical signals. Vibration is a different language so the signals are not precise or easily translatable. Also, there is no peer-reviewed research supporting the claims or the effectiveness of chest vibration in stimulating the vagus nerve. 

In contrast, Nurosym’s non-invasive ear clip design ensures targeted, gentle, and effective stimulation of the vagus nerve, delivering clinically proven benefits without discomfort or safety concerns. 

Unlike medications such as SSRIs which often come with side effects and focus solely on symptom management, Nurosym addresses the root cause by helping restore balance to the autonomic nervous system. Its safe and convenient design makes it suitable for daily use, offering a drug-free alternative to manage symptoms of chronic conditions like anxiety, POTS, and long COVID. 

With quick session times and proven efficacy, Nurosym is the clear choice for those seeking the best in vagus nerve stimulation therapy.

Take your health into your hands with Nurosym.

Simple, safe, and effective. Experience the power of clinically proven VNS technology right from the comfort of your own home.

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FAQ

Yes, Nurosym is at the forefront of clinical research, continuously investing substantial resources into furthering our understanding and application of neuromodulation technology. With over $10 million deployed in clinical trials, they're dedicated to advancing the science behind our certified medical device.

Nurosym collaborates with over 60 esteemed research organizations, including renowned institutions like Harvard and UCLU. Their commitment to transparency and excellence is underscored by their publication of over 30 papers in leading journals, such as Nature, showcasing the device’s exciting and clinically significant results.

It's important to note that all Nurosym studies are independently funded and led by investigators not affiliated with Nurosym. Most of the studies are randomized placebo-controlled trials, rigorously peer-reviewed, and published in high-quality scientific journals.

For those interested in delving deeper into Nurosym’s research, explore their Clinical Evidence page, where you can find comprehensive information on Nurosym studies. Healthcare professionals seeking additional insights into their studies, certification, or suggested treatment protocols can also reach out to them via email.

Nurosym stands as the most studied neuromodulation system of its kind, widely regarded as the gold standard in clinical neuromodulation research.

While the first vagus nerve stimulators were indeed placed around the neck, they required risky and precise surgery to target the vagus nerve specifically. Stimulating the vagus nerve around the neck without precision poses significant risks, including self-afflicted stroke and severe cardiac complications. Stimulating the right side of the neck has been associated with risks of severe cardiac adverse events, such as bradycardia or cardiac arrest.

For this reason, the FDA-approved labeling for vagal neuromodulation devices specifies that they should only stimulate the left vagus nerve in the neck area inside the carotid sheath, below where the superior and inferior cervical cardiac branches separate from the vagus nerve.

Additionally, Mayo Clinic researchers have warned in the leading scientific journal, Scientific American, that tampering with the vagus nerve with unlicensed medical devices can potentially result in cardiac arrest or sudden death.

On the other hand, Nurosym targets the vagus nerve via the ear (auricular branch). As the ear only contains sensory fibers of the vagus nerve, Nurosym’s proprietary Auricular Vagal Neuromodulation Therapy (AVNT) reaches the brain and activates the parasympathetic nervous system in the most natural and uniform way, overcoming the risks and limitations of neck stimulation.

As a CE-Marked medical device, Nurosym has undergone 30+ clinical trials with 60+ ongoing studies involving thousands of participants to validate its safety. There have been 0 severe adverse events reported across all studies. Nurosym is recommended by doctors around the world as the most studied vagal neuromodulation system globally.

As with any medical device, side effects are possible. However, we're happy to report that Nurosym is considered low risk when used as intended and boasts a very high safety profile. In fact, across all 30+ clinical studies conducted, there have been no reports of serious adverse events associated with Nurosym.

While side effects are rare, it's important to be aware of potential experiences. The most commonly reported side effects include:

  • Tingling on the skin where the electrode is applied (paresthesia/dysesthesia)
  • Discomfort on the skin of the ear (Application site discomfort)
  • Application site irritation/redness - if this occurs, try applying a bit of moisture before use, shorten session times, or switch ears
  • In the initial weeks of use, a small proportion of patients may also experience temporary effects that typically subside within 1-2 weeks of continuous use due to adaptation. These effects may include nausea, headaches, confusion, malaise, or weakness.

It's worth noting that in a published review of non-invasive neuromodulation clinical trials, only 2.6% of patients discontinued treatment due to side effects.

Nurosym can be a complementary tool alongside other treatments or medications for many individuals. However, there are specific contraindications to consider. These include:

  • Patients who have undergone surgery to cut the vagus nerve (cervical vagotomy)
  • Patients diagnosed with severe bradycardia
  • Patients with a permanent implanted metallic or electronic device or jewelry in close proximity to the ear tragus
  • Pregnant women

Additionally, certain situations may be contraindications unless under the supervision of a medical doctor, such as patients with any active implanted device, severe coronary disease or recent myocardial infarction within 5 years, and pediatric patients.

It's crucial to consult with your medical doctor to assess whether Nurosym is safe and appropriate for your specific circumstances, especially if you fall under any of these categories. Your doctor can provide guidance on potential precautions or supervision needed during Nurosym use. If you do not have a doctor you can contact, please reach out to our support and we’ll help connect you with the right person.

Getting started using your Nurosym is super easy.

  1. Apply a bit of moisture on the tragus (no gel needed)
  2. Wear the earpiece correctly on the tragus of your ear, the cable should go over and behind your ear to keep the electrodes in place.
  3. Press a button to turn on Nurosym
  4. Slowly increase energy level until you feel a light tingling sensation in your ear.
  5. Notice how pleasant the sensation of neuromodulation feels. This is a signal that the current is flowing and that your parasympathethic nervous system is activated.
  6. Perform normal daily activities while Nurosym works to strengthen your parasympathethic nervous system, decrease inflammation, oxidative stress and activate neuroplasticity to help you feel better.
  7. Notice the sensations of calmness, relaxation, decreased stress, improved mood, more energy flowing into your body.
  8. Continue using Nurosym every day for 30-60 minutes a day, preferably in the morning or split between morning after waking up and evening before sleep and enjoy better health & mood.

 

You can also watch a video of Dr. Denef explaining how to use Nurosym here.

Nurosym is versatile and convenient, allowing you to wear it during various activities such as reading, working, cooking, meditating, watching TV, or socializing. Simply press the button to activate. Using Nurosym during meditation enhances neuroplasticity, while during breathing sessions, it promotes relaxation and improves HRV. Before bed, it aids in better sleep, and in the morning, it releases tension and boosts energy. While working or studying, it enhances focus and learning and reduces tension. Additionally, you can use Nurosym as needed during or after stressful events or workouts to recover faster, during meals for digestion, or for pain relief.

Gradually increase the energy level until you feel a light tingling sensation, as this varies among individuals and may change day by day. Adjust the level during the session: increase if the sensation fades and decrease if it becomes too intense. The right level is when you feel the tingling without pain or discomfort in your tragus. If irritation occurs, shorten the stimulation time rather than lowering the energy level to ensure therapeutic effectiveness. As long as you feel the sensation without pain, you're using Nurosym correctly.

It’s not recommended to use Nurosym while sleeping or exercising due to safety considerations. It's important to use Nurosym in a controlled environment where you can remain aware of its effects. Always prioritize your safety and well-being when using Nurosym.

Nurosym is designed to be versatile and convenient, allowing you to wear it during various activities such as reading, working, cooking, meditating, watching TV, or socializing. We recommend incorporating Nurosym into your daily routine, aiming for 60 minutes per day to experience its beneficial effects, which can be felt in as little as 5 minutes. Using Nurosym before bed can help improve sleep quality. Additionally, you can use Nurosym as needed during or after stressful events or workouts to aid in faster recovery, during meals to assist with digestion, or for pain relief.

All Parasym clinical research has been conducted with each participant using their own personal device. To ensure the safest and most effective experience, they recommend that every individual user has their own device. Patient registration is done for each personal device to guarantee safe use.

If you do choose to share a device, it is strongly advised to use separate biocompatible components (such as earpieces) and ensuring that the other user is safe to use the technology.

Looking to purchase an extra earpiece? You can do so by clicking here.

No gel is required. A small amount of moisture, such as a drip of water, works well on the tragus. Conductive gel is also an option.

You'll know Nurosym is working for you if you can feel the sensation of neuromodulation without any pain. In terms of seeing results, initial results might be noticeable from as little as 5-10 days of use. However, it's important to use Nurosym consistently for relief and recovery from chronic autonomic dysregulation symptoms, which may take 4 to 12 weeks.

Nurosym Certifications & Authorisations

CE-marked non-invasive vagal neuromodulation system

EU Marketing authorisation

FDA NSR Designation

Nurosym by numbers

60+

Scientific Partners

3,000,000+

Sessions Completed

0

Serious Adverse Events in studies to date