A Silent Epidemic - The Unseen Struggles of Long COVID Patients
For millions around the world, COVID-19 was only the beginning. Long after the acute infection, an alarming number of individuals continue to suffer from persistent, life-altering symptoms—fatigue, brain fog, shortness of breath, heart palpitations, and a profound sense of disconnection from their own bodies.
Many have sought answers, only to be dismissed or told their symptoms are “psychosomatic."
The medical community remains perplexed, as no universally accepted treatment has emerged. But promising research now suggests that a crucial piece of the puzzle may lie in one of the body’s most vital yet overlooked systems: the vagus nerve.
The Vagus Nerve - A Key Player in Long COVID
The vagus nerve is the main communication highway of the parasympathetic system, regulating involuntary functions like heart rate, digestion, immune response, and inflammation.
Emerging research suggests that COVID-19 may impair vagus nerve function, leading to dysautonomia, an imbalance in the autonomic nervous system.
This dysfunction creates a ripple effect:
- Fatigue and cognitive dysfunction arise from impaired autonomic regulation, affecting energy levels and mental clarity.
- Shortness of breath results from dysregulated respiratory control, making even simple activities exhausting.
- Headaches are linked to persistent inflammation and autonomic dysfunction, intensifying discomfort and brain fog.
For those suffering from Long COVID, restoring vagal function could be a breakthrough—one that might finally offer relief.
From Surgery to The End of Invasive Vagus Nerve Treatments
In the past, correcting vagus nerve imbalance required surgical implants — a costly and invasive solution.
But after 10 years of research and over $10 million invested, Parasym developed a breakthrough: Nurosym™, the world’s first non-invasive, wearable vagus nerve stimulation device. It delivers targeted neuromodulation through the ear, helping to reset nervous system balance — without surgery, medication, or downtime.
The Non-Invasive Method: Auricular Vagal Neuromodulation Therapy (AVNT™)
Parasym, a pioneer in bioelectric medicine, has developed Nurosym, a non-invasive auricular vagal nerve stimulation (AVNS) device. Clinical trials now show that stimulating the vagus nerve via the ear can restore autonomic balance, reduce inflammation, and improve Long COVID symptoms.
Nurosym’s technology delivers gentle electrical impulses to the auricular branch of the vagus nerve, triggering the body’s cholinergic anti-inflammatory pathway—a natural mechanism that dampens excessive immune responses.
Scientific Evidence - The First Promising Results
Recent clinical trials using Nurosym’s technology have shown remarkable improvements:
- 61% reduction in Long COVID symptoms, including brain fog and fatigue.
- 48% reduction in fatigue, offering patients renewed energy.
- 35% decrease in anxiety, a common Long COVID symptom.
- 40% reduction in POTS-related tachycardia, improving cardiovascular function.
- 78% reduction in inflammation, addressing a core issue in Long COVID pathology.
These findings reinforce what many researchers have suspected—targeting the vagus nerve can help rebalance the nervous system and accelerate recovery.
Single Clinical Study Showed:
40%
Improvement in Inflammation
*In a clinical trial, a very significant improvement in Long-COVID symptoms was observed after 10 neuromodulation therapy sessions..
Read Study
"It has helped to calm my nervous system down, resulting in drastic decrease of brainfog"
In another trial, researchers focused on tracking energy levels using Pichot Fatigue score:
Single Clinical Study Showed:
48%
Reduced Fatigue & Increased Energy
*In the study, patients reported sustained improvements even one week after discontinuing the therapy, indicating prolonged relief from fatigue-related symptoms.
Read Study
"Today I started running again for the first time in two years."
In a third trial, researchers measured inflammatory cytokines and saw significant improvement in pain management:
Single Clinical Study Showed:
61%
Improvement in Inflammation
*In a randomised controlled trial, inflammatory cytokines were significantly lower in the group that received Auricular Vagal Neuromodulation Therapy (AVNT) compared to the placebo group at the end of 3 months.
Read Study
"Since I started using it, I sleep very well every night, I have much less pain, and I have been able to return to part-time work"
Beyond the Data - Real Stories of Recovery
Behind the statistics are real patients who have regained their quality of life. One case study describes a 28-year-old man with persistent Long COVID symptoms—chronic fatigue, palpitations, and mental fog—that left him unable to work.
After months of failed treatments, he tried Nurosym and noticed a significant improvement in energy, mental clarity, and cardiovascular stability within weeks.
“There is no trial of any drug or anything I’ve ever done in all my years that makes a patient so well that he or she no longer fulfills criteria for chronic fatigue syndrome,” says Benjamin Natelson, a neurologist at Mount Sinai, who has run several clinical studies on vagus nerve stimulation for various health conditions (Scientific American).
Dr Mikolaj Raszek, clinical researcher for Long COVID, finds that "based on the evidence coming out, it looks as if these devices... appear to be helping big time in terms of Post-Viral Fatigue."
Another patient, a 30-year-old woman suffering from POTS after COVID-19, found that daily use of Nurosym stabilized her heart rate and reduced dizziness, allowing her to resume normal activities.
Nurosym user reviews have also been overwhelmingly positive:
"I have Long Covid since over 4 years and my main issues are brainfog, PEM, fatigue and MCAS/IBS. The Nurosym device has been a gamechanger"
"I’m starting to have a bit more energy each day and have been able to accomplish simple tasks that I could not begin to start 6 months ago!"
Why this approach is different
Unlike many symptom-based treatments that only provide temporary relief, neuromodulation works by addressing the root cause—the autonomic imbalance and inflammation driving Long COVID.
- Non-invasive & drug-free: Unlike medications with potential side effects, Nurosym is safe, well-tolerated, and easy to use at home.
- Backed by rigorous science: Nurosym has undergone over 50 peer-reviewed clinical studies and 4 million treatment sessions.
- Validated for dysautonomia-related conditions: Research shows efficacy in anxiety, inflammation, and cognitive function, making it a promising tool for Long COVID sufferers.
Why Nurosym Stands Apart
In the growing field of vagus nerve stimulation (VNS), Nurosym™ leads with unmatched scientific credibility, safety, and clinical performance. Backed by years of research, trusted by leading institutions, and used by thousands of professionals and patients alike, here’s why Nurosym is considered the gold standard in non-invasive neuromodulation.
Proven by Science
Nurosym is the most studied non-invasive vagus nerve neuromodulation system in the world, with:
- 50+ clinical studies conducted in collaboration with top-tier research institutions.
- 60+ research partnerships, including with Harvard, UCLA, and Yale.
Built for Safety
When it comes to wearable VNS devices, Nurosym is the safest available:
- CE-marked as a certified medical device.
- Zero serious adverse events reported in studies to date.
Engineered for Results
Nurosym isn’t just safe — it’s remarkably effective:
- Clinically proven to deliver a 50% increase in vagus nerve activity within just 5 minutes.
- Found to be 3–4x more effective than breathing exercises or meditation at activating the parasympathetic system.
- Fastest way to activate the vagus nerve in a non-invasive format.
Trusted by Healthcare Professionals
Nurosym is the #1 doctor-recommended wearable VNS, with:
- Over 1,000 healthcare professionals recommending it to their patients.
- More than 4 million successful user sessions completed globally.
Beware of Imitations
As vagus nerve stimulation gains traction, many unregulated devices have entered the market. Unlike Nurosym, these products lack clinical validation and may fail to deliver effective results. Parasym’s technology is CE-marked medical device and designated FDA Non-Significant Risk, ensuring both safety and efficacy.
Join the Research – €100 Subsidy Toward Your Device
To further expand this research, Parasym is inviting Long COVID patients to participate in ongoing clinical trials. Participants can receive €100 off Nurosym as part of the study.
If you’ve struggled with Long COVID and conventional treatments haven’t worked, this could be the breakthrough you’ve been waiting for.
Plus, every device comes with a 30-day money-back guarantee — so you can try Nurosym risk-free and see if it helps you feel more like yourself again.
Closing Thoughts - Hope for Long COVID Patients
For too long, Long COVID patients have faced uncertainty, dismissal, and frustration. But science is finally catching up. Neuromodulation offers a real, tangible path to recovery, restoring balance where the body’s own systems have gone awry.
As research continues to unfold, one thing is clear: the vagus nerve may hold the key to unlocking lasting relief from Long COVID.
If you or a loved one is struggling with persistent symptoms, it’s time to explore a science-backed solution that is changing lives.
Dr. Greta Dalle Luche, PhD
User Stories and Results
- Long-Covid Symptoms
Relieving Long COVID Symptoms
Five star rating for me. In this world where there's not much we can go on, this is one of the things we can.
Derek
- Inflammation
- Chronic Fatigue
- Sleep issues
Post Viral Fatigue, Autoimmune Relief and Better Sleep
“I definitely noticed when I haven't used it, I don't sleep as well.”...”when I don't use it, I feel a lot more inflamed and achy and just not well.”
Kate
- Axiety
- Depression
- Oxidative Stress
- Sleep issues
Conquering Stress, Depressive States, and Anxious Thoughts: A Personal journey
"I just love it. I use it on a daily basis. It makes me sleep better, feel better. I would recommend it to everyone."
Tijana
- Gastrointestinal symptoms
Irritable Bowel Syndrome (IBS), Bloating, Gas, and Nausea No More
“I ordered it online, and I can honestly say, within a few days of using it, the symptoms disappeared.”
Lucy
- Stress
- Anxious Thoughts
Boosting Relaxation and Reducing Negative Thoughts
“I would wholeheartedly recommend the Nurosym wearable device for anyone who may be having difficulty with stress, who wants to increase their own well-being and peace of mind.”
Jordan
- Fatigue
- Brain Fog
From Fatigue, Menstrual Pain to Clarity
"I've had a very good experience with it, and I'd recommend it to anybody who was hoping for relief, particularly from chronic tiredness and brain fog symptoms."
Tasha
- Vagus Nerve Activity
- Heart Rate Variability
- Oxidative Stress
Improving Heart Rate Variability and Relieving Stress
“The Nurosym seems to have had a positive impact on myself. Am I feeling a little bit less stressed? Yes. So I’m happy to say that the intervention seems to have been effective.”
Doctor James Gill
- Recovery
- Heart Rate Variability
- Sleep
Boosting Recovery & Reaching Peak Performance More Easily
“For me I’ve always struggled with my recovery.”...“But now with Nurosym, I’m able to get to my best scores every single day using Nurosym.”
Tanya
Try risk-free for 30 days
Experience Nurosym at home and return it for a full refund if you don't love it
Certified medical device
Resets your resting state for deeper sleep and more daily energy
Worry-free warranty
Ongoing device protection for up to 5 years.
We ship to all EU countries & UK and selected countries worldwide. If you can check out on our website, you can assume we can ship to you. We ship from Netherlands. You should receive your device within a few days after shipping depending on your location. There should not be any extra costs if you are inside the EU. If you are outside of the EU, you may be liable for import fees, which are out of our control.