Nervous System Dysregulation: The Silent Pandemic You’ve Never Heard of

In recent years, conditions such as chronic fatigue, anxiety, and functional gastrointestinal disorders have been on the rise, leading to a myriad of physical, emotional, and social problems for millions of people around the globe. Despite seeking help from multiple doctors and trying various treatments, many patients find themselves without a lasting solution for their specific issues [1].

However, recent scientific findings revealed that the underlying cause of numerous physical and mental health issues might lie in the nervous system [2].

Our bodies are designed to keep us alive and healthy by managing the daily stressors we encounter. To do this, the nervous system operates through two key components: the sympathetic system (fight or flight), which helps us gear up to handle challenges, and the parasympathetic system (rest & digest), which helps us recover and restore balance. Both systems are necessary and, when properly balanced, work in harmony to help us adapt to life’s challenges with peace and tranquility [3].

However, when the body is exposed to chronic stress, this balance is disrupted. Instead of adapting, the nervous system becomes overwhelmed, leading to excess cortisol, increased inflammation, and damage to various organ systems. This dysregulation not only impairs the immune system and digestive functioning, but can also cause brain fog, fatigue, anxiety, and a host of other issues that can affect nearly every aspect of life [4].

The key to addressing the widespread health issues across our modern world is not just targeting specific symptoms or organs, but rather focusing on improving the cooperation between various organs by regulating the nervous system. By restoring balance between the sympathetic and parasympathetic systems, we can help the body activate its natural restoration mechanisms and function optimally, as it was meant to [4]. 

Selective and Safe Vagus Nerve Stimulation

The vagus nerve is a complex and multifaceted nerve, originating in the brainstem and extending through the neck into the abdomen, innervating multiple organs along the way. It plays a crucial role in regulating the autonomic nervous system, heart rate, gastrointestinal function, immune response, and mood. This vast network of functions is controlled by approximately 100,000 fibers within the vagus nerve, each with specific roles. In VNS, electrical impulses aim to target these specific fibers to project signals to the brain and other organs, eliciting therapeutic responses for conditions such as epilepsy, depression, heart disease, and inflammatory diseases [13].

However, targeting the right fibers poses significant challenges. Safety is paramount, as the vagus nerve controls all major organs. Targeting is also complicated due to the nerve's various accessible points, such as the neck and ear. The neck, a site containing both sensory and motor fibers, poses risks of erratic signals leading to side effects like palpitations. Conversely, the auricular branch in the ear, primarily composed of sensory fibers, provides a more uniform and natural activation of the parasympathetic nervous system. The tragus of the ear has been found to be particularly suitable for such stimulation, as it has the highest density of afferent vagus nerve fibers closest to the skin surface [14].

Modulation vs Stimulation

When it comes to the vagus nerve, more stimulation doesn’t necessarily mean better results. Coming back to the radio analogy—finding specific frequency without knowing any details is challenging. Similarly, everyone's nervous system is unique, requiring precise control and adjustment to match its current state, which can vary day by day and from person to person. Similarly to excessive stress, excessive stimulation of the vagus nerve can also push the delicate nervous system out of balance. This can lead to unpleasant side effects or even permanent damage to the vagus nerve.

This is why it is important to use only certified medical devices with rigorously tested signals. Your vagus nerve is too precious to play risky games with it.

Nurosym is a certified medical device that underwent a myriad of safety studies and has met the requirements of EU regulators, which ensures safety of our current good manufacturing standards to make sure every device is carefully inspected and tested. Nurosym has also been evaluated by the FDA as a Non Significant Risk device in multiple clinical trials.

Nurosym also offers precise modulation settings with 45 energy levels, allowing for tailored adjustments that ensure optimal effectiveness and safety for each individual’s nervous system.

Convenience: Vagus Nerve stimulation without gel

Normally, applying current to the skin requires a conductivity gel because the skin’s electrical resistance varies constantly. However, using a gel can be inconvenient and messy, especially for regular use. After 10 years of clinical research, Nurosym scientists developed a neuromodulation system that effectively overcomes this challenge. By employing a hypoallergenic material with high conductivity and biocompatibility, the system ensures efficient current transmission through the skin, while minimizing irritation or risk of damage without having to use any gel.

Nurosym is the most clinically studied non-invasive auricular vagal neuromodulation device. 

Validated by over 40 peer-reviewed clinical studies over 10 years of research and development conducted in collaboration with leading clinical research institutions such as Harvard, UCLA and several NHS hospitals, Nurosym offers safe and precise modulation of the vagus nerve right in the palm of your hand. It’s also the first CE-marked non-invasive auricular vagal neuromodulation device to reach the consumer market.

Nurosym works by using proprietary Auricular Vagal Neuromodulation Therapy (AVNT) to send patented micro impulses through to the leftto left ear tragus to precisely and effectively target the vagus nerve.

Functional MRI studies show that this location achieves the most selective activation of the vagus nerve pathways, while also providing superior vagal activation. Meanwhile, the lack of precision in other potential sites can interfere with other neural pathways, resulting in side effects that may cause permanent damage [15].